This is the list of singles that reached number one on the Cash Box Top 100 Singles chart in 1982, presented in chronological order.
| Issue Date | Song | Artist |
| January 2 | "Physical" | Olivia Newton-John |
| January 9 | "Physical" | Olivia Newton-John |
| January 16 | "I Can't Go for That (No Can Do)" | Daryl Hall and John Oates |
| January 23 | "I Can't Go for That (No Can Do)" | Daryl Hall and John Oates |
| January 30 | "Centerfold" | The J. Geils Band |
| February 6 | "Centerfold" | The J. Geils Band |
| February 13 | "Centerfold" | The J. Geils Band |
| February 20 | "Centerfold" | The J. Geils Band |
| February 27 | "Centerfold" | The J. Geils Band |
| March 6 | "Centerfold" | The J. Geils Band |
| March 13 | "Open Arms" | Journey |
| March 20 | "I Love Rock 'n Roll" | Joan Jett and the Blackhearts |
| March 27 | "I Love Rock 'n Roll" | Joan Jett and the Blackhearts |
| April 3 | "That Girl" | Stevie Wonder |
| April 10 | "I Love Rock 'n Roll" | Joan Jett and the Blackhearts |
| April 17 | "I Love Rock 'n Roll" | Joan Jett and the Blackhearts |
| April 24 | "I Love Rock 'n Roll" | Joan Jett and the Blackhearts |
| May 1 | "Chariots of Fire" | Vangelis |
| May 8 | "Chariots of Fire" | Vangelis |
| May 15 | "Ebony and Ivory" | Paul McCartney and Stevie Wonder |
| May 22 | "Ebony and Ivory" | Paul McCartney and Stevie Wonder |
| May 29 | "Ebony and Ivory" | Paul McCartney and Stevie Wonder |
| June 5 | "Ebony and Ivory" | Paul McCartney and Stevie Wonder |
| June 12 | "Ebony and Ivory" | Paul McCartney and Stevie Wonder |
| June 19 | "Ebony and Ivory" | Paul McCartney and Stevie Wonder |
| June 26 | "Don't You Want Me" | The Human League |
| July 3 | "Don't You Want Me" | The Human League |
| July 10 | "Don't You Want Me" | The Human League |
| July 17 | "Don't You Want Me" | The Human League |
| July 24 | "Hurts So Good" | John Cougar |
| July 31 | "Eye of the Tiger" | Survivor |
| August 7 | "Eye of the Tiger" | Survivor |
| August 14 | "Eye of the Tiger" | Survivor |
| August 21 | "Eye of the Tiger" | Survivor |
| August 28 | "Abracadabra" | Steve Miller Band |
| September 4 | "Abracadabra" | Steve Miller Band |
| September 11 | "Abracadabra" | Steve Miller Band |
| September 18 | "Abracadabra" | Steve Miller Band |
| September 25 | "Abracadabra" | Steve Miller Band |
| October 2 | "Jack and Diane" | John Cougar |
| October 9 | "Jack and Diane" | John Cougar |
| October 16 | "Jack and Diane" | John Cougar |
| October 23 | "Who Can It Be Now?" | Men at Work |
| October 30 | "Who Can It Be Now?" | Men at Work |
| November 6 | "Up Where We Belong" | Joe Cocker and Jennifer Warnes |
| November 13 | "Up Where We Belong" | Joe Cocker and Jennifer Warnes |
| November 20 | "Up Where We Belong" | Joe Cocker and Jennifer Warnes |
| November 27 | "Gloria" | Laura Branigan |
| December 4 | "Truly" | Lionel Richie |
| December 11 | "Truly" | Lionel Richie |
| December 18 | "Maneater" | Daryl Hall and John Oates |
| December 25 | "Maneater" | Daryl Hall and John Oates |
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